TGFBR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142789-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142789 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
TGFBR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TGFBR1
Gene Alias
AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
29591, 7046
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P36897, P80204
Gene Symbols
TGFBR1
Immunogen
Peptide with sequence TDGLCFVSVTETTD.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize both reported isoforms (NP_004603.1; NP_001124388.1)
- The immunizing peptide represents part of a potential extracellular domain
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000
- This antibody is not recommended for ICC/IF
- TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs
- Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1
- TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm
- The encoded protein is a serine/threonine protein kinase
- Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).