PIPA5142796
Thyroid Peroxidase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142796-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142796 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
Thyroid Peroxidase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TPO
Gene Alias
EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
7173
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P07202
Gene Symbols
TPO
Immunogen
Peptide with sequence ELRCGKHQAVGTSPQ.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize all reported isoforms (NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1)
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
- Thyroid Peroxidase is a gene that encodes for a membrane-bound glycoprotein, which functions as an enzyme and plays a crucial role in the proper functioning of the thyroid gland
- This protein is responsible for the iodination of tyrosine residues in thyroglobulin and the formation of phenoxy-ester between pairs of iodinated tyrosines, which leads to the production of thyroid hormones such as thyroxine and triiodothyronine
- Mutations in this gene are known to cause several disorders related to thyroid hormone production, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA
- Several transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants remains undetermined
- Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.