PCNA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142926-Each-of-1 | In Stock | ₹ 41,874.50 |
PIPA5142926 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,874.50
GST (18%): ₹ 7,537.41
Total Price: ₹ 49,411.91
Antigen
PCNA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pcna
Gene Alias
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
18538, 25737, 5111, 692192
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P04961, P12004, P17918
Gene Symbols
Pcna
Immunogen
Peptide with sequence C-NGNIKLSQTSNVD.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine, Rat
Form
Liquid
Related Products
Description
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
- PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways
- PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT)
- PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e
- relevant to prognosis)
- PCNA is a marker for cells in early G1 phase and S phase of the cell cycle
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication
- In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway
- Two transcript variants encoding the same protein have been found for PCNA
- Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.