PIPA5143242

CNGB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143242-Each-of-1 In Stock ₹ 40,317.00

PIPA5143242 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

CNGB3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CNGB3

Gene Alias

ACHM1; cng channel; CNG channel beta-3; CNGB3; cone photoreceptor cGMP-gated cation channel beta-subunit; Cone photoreceptor cGMP-gated channel subunit beta; cyclic nucleotide gated channel beta 3; cyclic nucleotide-gated cation channel beta-3; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-3

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

54714

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9NQW8

Gene Symbols

CNGB3

Immunogen

Peptide with sequence C-ESDDKPTEHYYR.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000
  • Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger
  • This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors
  • Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3
  • Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.