Vinculin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA514325-Each-of-1 | In Stock | ₹ 48,816.50 |
PIPA514325 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,816.50
GST (18%): ₹ 8,786.97
Total Price: ₹ 57,603.47
Antigen
Vinculin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
VCL
Gene Alias
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
22330, 305679, 7414
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P18206, P85972, Q64727
Gene Symbols
VCL
Immunogen
KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human VINC
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
Ig
Related Products
Description
- This antibody is predicted to react with chicken, porcine and rat based on sequence homology
- Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions
- It functions as one of several interacting proteins involved in anchoring F-actin to the membrane
- It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques
- In the assembly of adhesion plaques, the beta subunit of integrin binds to talin
- Talin binds to vinculin that interacts with alpha-actinin and possibly with itself
- Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system
- Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.