PIPA5143274

IFITM3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143274-Each-of-1 In Stock ₹ 40,317.00

PIPA5143274 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

IFITM3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFITM3

Gene Alias

1110004C05Rik; 1-8U; Cd225; Cdw217; Dispanin subfamily A member 2b; DSPA2b; Fgls; Fragilis; Fragilis 3; Fragilis protein; Ifitm3; ifitm-like protein 1; interferon induced transmembrane protein 3; interferon-induced transmembrane protein 3; interferon-inducible protein 15; Interferon-inducible protein 1-8U; interferon-inducible protein variant 10; IP15; mil-1; Mouse ifitm-like protein 1; rat8

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

10410

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q01628

Gene Symbols

IFITM3

Immunogen

Peptide with sequence HTVQTFFSPVNS-C.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000
  • IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins
  • IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions
  • IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes
  • Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons
  • In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis
  • Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma
  • IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.