PIPA5143494

SARS-CoV-2 NSP5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143494-Each-of-1 In Stock ₹ 39,071.00

PIPA5143494 - Each of 1

₹ 39,071.00

In Stock

Quantity

1

Base Price: ₹ 39,071.00

GST (18%): ₹ 7,032.78

Total Price: ₹ 46,103.78

Antigen

SARS-CoV-2 NSP5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ORF1ab

Gene Alias

COVID-19 Envelope; SARS-CoV-2; SARS-CoV-2 Envelope

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

43740578

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1.5 mg/mL

Formulation

PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Gene Accession No.

P0DTD1

Gene Symbols

ORF1ab

Immunogen

Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) 3CLpro (nsp5). The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Virus

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • SARS-CoV-2 NSP5 is a non-structural protein in which the main protease targets RIG-I and mitochondrial antiviral signaling (MAVS) protein via two distinct mechanisms for inhibition
  • NSP5 cleaves off the 10 most-N-terminal amino acids from RIG-I and deprives it of the ability to activate MAVS, whereas NSP5 promotes the ubiquitination and proteosome-mediated degradation of MAVS
  • NSP5 potently inhibits interferon (IFN) induction by double-stranded RNA (dsRNA) in an enzyme-dependent manner.