alpha Synuclein Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143547-Each-of-1 | In Stock | ₹ 1,46,494.00 |
PIPA5143547 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,46,494.00
GST (18%): ₹ 26,368.92
Total Price: ₹ 1,72,862.92
Antigen
alpha Synuclein
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SNCA
Gene Alias
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)
Host Species
Chicken
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100053270, 20617, 282857, 29219, 641350, 6622
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
O55042, P37377, P37840, Q3I5G7, Q3T0G8
Gene Symbols
SNCA
Immunogen
Full length recombinant human protein expressed in and purified from E. coli
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Equine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgY
Related Products
Description
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
- These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
- Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
- Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
- Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
- Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
- Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.