PIPA5143597

Cas12j Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143597-Each-of-1 In Stock ₹ 42,675.50

PIPA5143597 - Each of 1

₹ 42,675.50

In Stock

Quantity

1

Base Price: ₹ 42,675.50

GST (18%): ₹ 7,681.59

Total Price: ₹ 50,357.09

Antigen

Cas12j

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

Cas theta

Immunogen

Full length Cas12j expressed in and purified from E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Target Molecule

Chemical

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG

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Description

  • There has been much recent interest in gene editing and other genetic manipulations by CRISPR-Cas family enzymes
  • The lab of Nobel prize winner Jennifer Doudna characterized these Cas enzymes and showed that they could be used to perform CRISPR, but had the significant advantage that they were much smaller in molecular size than other Cas family enzymes such as the widely used Cas9 enzymes from S
  • pyogenes and S
  • aureus
  • One of these enzymes is referred to as Cas theta and also known as Cas-12j
  • The use of such smaller Cas family enzymes leaves more room for other nucleic acid sequences in AAV and other viral vectors which typically have a limited DNA capacity, thus allowing more versatility for new CRISPR based manipulations.