PIPA5143831

SARS-CoV-2 ORF3a Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143831-Each-of-1 In Stock ₹ 38,181.00

PIPA5143831 - Each of 1

₹ 38,181.00

In Stock

Quantity

1

Base Price: ₹ 38,181.00

GST (18%): ₹ 6,872.58

Total Price: ₹ 45,053.58

Antigen

SARS-CoV-2 ORF3a

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OMD

Gene Alias

COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A

Immunogen

A peptide corresponding to 15 amino acids near the amino-terminus of SARS-CoV-2 (COVID-19) ORF3a protein. The immunogen is located within the first 50 amino acids of the SARS-CoV-2 (COVID-19) ORF3a protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Virus

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q99983

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4958

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release
  • Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells
  • Induces apoptosis in cell culture
  • Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.