KLF10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143901-Each-of-1 | In Stock | ₹ 35,422.00 |
PIPA5143901 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,422.00
GST (18%): ₹ 6,375.96
Total Price: ₹ 41,797.96
Antigen
KLF10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KLF10
Gene Alias
AI115143; Cpg20; early growth response-alpha; EGR[a]; EGRA; Egral; EGR-alpha; Gdnfif; GDNF-inducible factor; Klf10; Krueppel-like factor 10; Kruppel like factor 10; Kruppel-like factor 10; mGIF; TGFB inducible early growth response; TGFB inducible early growth response 1; TGFB-inducible early growth response protein 1; Tieg; TIEG1; TIEG-1; transcription factor GIF; Transforming growth factor-beta-inducible early growth response protein 1; zinc finger transcription factor homolog CPG20; zinc finger transcription factor TIEG
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7071
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and no preservative
Gene Accession No.
Q13118
Gene Symbols
KLF10
Immunogen
E.coli-derived human KLF10 recombinant protein (Position: K36-A471).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
Related Products
Description
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
- KLF10 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers
- KLF10 is a transcriptional repressor involved in the regulation of cell growth and inhibits cell growth
- It binds to the consensus sequence 5'-GGTGTG-3' and is induced by TGF-beta thus playing a role in linking TGF-beta-mediated signaling cascades to the regulation of pancreatic epithelial cell growth
- KLF10 is involved in inducing and promoting apoptosis through the mitochondrial apoptotic pathway and may inhibit Smad7 expression in bronchial epithelial cells
- Ubiquitous expression of KLF10 is seen in most of the tissues
- Reports suggest that it may mediate up-regulation of TGFBI in VHL-deficient tumors and other cancers
- Over expression of KLF10 may be associated with renal clear cell carcinoma and other tumors
- KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters
- This binding inhibits cell growth and causes apoptosis
- Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7)
- Three transcript variants encoding two different isoforms have been found for this gene.