CD101 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143965-Each-of-1 | In Stock | ₹ 35,422.00 |
PIPA5143965 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,422.00
GST (18%): ₹ 6,375.96
Total Price: ₹ 41,797.96
Antigen
CD101
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD101
Gene Alias
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9398
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Applications
ELISA, Immunohistochemistry (Paraffin)
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and no preservative
Gene Accession No.
Q93033
Gene Symbols
CD101
Immunogen
E.coli-derived human CD101 recombinant protein (Position: E53-A904).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
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Description
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
- CD101 also known as V7 antigen, a member of the Ig superfamily
- CD101 is a disulfide linked homodimer of unknown function
- Expression of CD101 is found on monocytes, granulocytes and dendritic cells (Langerhan-like cells HLA-DR, CD1a, CD1c)
- In addition expression on T lymphocytes is important for cell activation
- CD101+ CD28+ cells are very responsive to CD28 signaling
- In combination with anti-CD28 or suboptimal levels of anti-CD3, anti-CD101 can increase proliferation thereby suggesting an activating role
- The monoclonal antibody BB27 has been shown to inhibit the T cell reactivity in allogeneic and antigen-specific mixed DC-T cell cultures
- Recently it has been demonstrated that mouse CD101 is found on a subpopulation of regulatory T cells (CD4, CD25, Foxp3 positive) that have high suppressor activity
- Expression of CD101 on human PBMCs shows staining of about 30% of the Foxp3 positive cells
- Studies have not confirmed higher suppressor activity in the human CD101 population.