mGluR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519348-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA519348 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
mGluR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRM2
Gene Alias
4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; GLUR2; glutamate metabotropic receptor 2; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; GPRC1B; Grm2; M mGlu2; Metabotropic; Metabotropic glutamate receptor 2; mGlu2; MGLUR2; mGluR7
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
2912
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q14416
Gene Symbols
GRM2
Immunogen
Synthetic peptide sequence (KETAPERREV) corresponding to the internal amino acids of GRM2
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine, canine, mouse, rabbit and rat based on sequence homology
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000
- Glutamate is the main excitatory neurotransmitter in the brain
- For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission
- Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins
- These receptors are called metabotropic glutamate receptors
- In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores
- Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase
- The Group-I receptors include mGluR1a and mGluR5
- The Group-II receptors in include mGluR2 and mGluR3.