PIPA519451

Phospho-GluR1 (Thr840) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519451-Each-of-1 In Stock ₹ 42,898.00

PIPA519451 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

Phospho-GluR1 (Thr840)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Accession No.

P23818, P19490

Gene Symbols

GRIA1

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 850 to the C-terminus of Mouse Glutamate Receptor 1 (AMPA subtype), phosphorylated at pThr840

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration

0.4 mg/mL

Gene

Gria1

Gene Alias

GLUH1, GLUR1, GLURA, GluA1, HBGR1, MGC133252, AMPA 1; AMPA-selective glutamate receptor 1; gluR-1; gluR-A; gluR-K1; glutamate receptor 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14799, 50592

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody is predicted to react with human based on sequence homology
  • GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor
  • L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system
  • Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse
  • Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist
  • In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.