PIPA519474

PADI2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519474-Each-of-1 In Stock ₹ 52,065.00

PIPA519474 - Each of 1

₹ 52,065.00

In Stock

Quantity

1

Base Price: ₹ 52,065.00

GST (18%): ₹ 9,371.70

Total Price: ₹ 61,436.70

Antigen

PADI2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PADI2

Gene Alias

KIAA0994; mKIAA0994; PAD type II; Pad2; PAD-H19; PADI2; Pdi; PDI2; peptidyl arginine deiminase 2; peptidyl arginine deiminase, type 2; peptidyl arginine deiminase, type II; peptidyl arginine deiminase, type II; PAD type II; peptidylarginine deiminase II; Protein-arginine deiminase type II; protein-arginine deiminase type-2; RP1-37C10.6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11240, 29511

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.9 mg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide; pH 7.4

Gene Accession No.

P20717, Q9Y2J8

Gene Symbols

PADI2

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human PADI2 / PAD2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • For Western Blot, this antibody has non-specific bands at 34 kDa
  • Heat mediated antigen retrieval recommended prior to tissue staining
  • This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions
  • The family members have distinct substrate specificities and tissue-specific expression patterns
  • The type II enzyme is the most widely expressed family member
  • Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages
  • This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis
  • This gene exists in a cluster with four other paralogous genes.