PIPA519663

SFPQ Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519663-Each-of-1 In Stock ₹ 46,502.50

PIPA519663 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SFPQ

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SFPQ

Gene Alias

100 kDa DNA-pairing protein; 1110004P21Rik; 2810416M14Rik; 5730453G22Rik; 9030402K04Rik; AU021830; D4Ertd314e; DNA-binding p52/p100 complex, 100 kDa subunit; Gm12940; hPOMp100; NonO/p54nrb homolog; OTTMUSG00000009329; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; polypyrimidine tract-binding protein-associated-splicing factor; POMP100; PPP1R140; protein phosphatase 1, regulatory subunit 140; PSF; PTB-associated splicing factor; PTB-associated-splicing factor; REP1; Sfpq; splicing factor proline and glutamine rich; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated); splicing factor proline/glutamine-rich; splicing factor, proline- and glutamine-rich

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

252855, 6421, 71514

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.6 mg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide; pH 7.4

Gene Accession No.

P23246, Q8VIJ6

Gene Symbols

SFPQ

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 650 to the C-terminus of Human SFPQ.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with rat and zebrafish based on sequence homology
  • SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression
  • SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program
  • Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD
  • SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types.