FLIP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519881-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA519881 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
FLIP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CFLAR
Gene Alias
2310024N18Rik; A430105C05Rik; Cash; CASP8 and FADD like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator subunit p12; CASP8 and FADD-like apoptosis regulator subunit p43; CASP8AP1; caspase homolog; Caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; Cellular FLICE-like inhibitory protein; Cflar; c-Flip; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; ENSMUSG00000072980; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; Flip; Gm9845; I-FLICE; Inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; usurpin; usurpin beta
Host Species
Rabbit
Purification Method
Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12633
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O35732
Gene Symbols
CFLAR
Immunogen
A peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot applications, this antibody detects a band at ∽55kDa
- A suggested positive control is NIH-3T3 cell lysate
- PA5-19881 can be used with blocking peptide PEP-0013
- FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells
- It acts as an inhibitor of TNFRSF6 mediated apoptosis
- A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex
- Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis
- Lacks enzymatic (caspase) activity.