PHAP III Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520023-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA520023 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
PHAP III
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ANP32A
Gene Alias
2810018A15Rik; Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member E; Acidic leucine-rich nuclear phosphoprotein 32 family member E-like protein; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein pp32; AI047746; AI326868; Anp32; Anp32a; Anp32e; C15orf1; cerebellar leucine rich acidic nuclear protein; cerebellar postnatal development protein 1; Cpd1; hepatopoietin Cn; HPPCn; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; LANPL; LANP-L; LANP-like protein; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; leucine-rich acidic nuclear protein like;
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11737, 25379, 8125
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O35381, P39687, P49911
Gene Symbols
ANP32A
Immunogen
A synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot applications, this antibody detects a band at ∽35kDa
- A suggested positive control is A549 cell lysate
- PA5-20023 can be used with blocking peptide PEP-0142
- Apoptosis is related to many diseases and development
- Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators
- Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9
- Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis
- The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis
- PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway
- PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.