ARMER Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520061-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA520061 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
ARMER
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARL6IP1
Gene Alias
ADP ribosylation factor like GTPase 6 interacting protein 1; ADP-ribosylation factor GTPase 6 interacting protein 1; ADP-ribosylation factor like GTPase 6 interacting protein 1; ADP-ribosylation factor-like 6 interacting protein; ADP-ribosylation factor-like 6 interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1-like protein; ADP-ribosylation-like factor 6 interacting protein; ADP-ribosylation-like factor 6-interacting protein; AIP1; aip-1; AIP-6; AL022945; apoptotic regulator in the membrane of the endoplasmic reticulum; ARL-6-interacting protein 1; Arl6ip; arl6ip protein; Arl6ip1; ARMER; AU042858; C85138; KIAA0069; mKIAA0069; Protein TBX2; SPG61; zgc:56593; zgc:77873
Host Species
Rabbit
Purification Method
Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23204, 54208
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q15041, Q9JKW0
Gene Symbols
ARL6IP1
Immunogen
A peptide corresponding to 15 amino acids near the C-terminus of human ARMER.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse small intestine tissue lysate
- PA5-20061 can be used with blocking peptide PEP-0180
- Apoptosis is important for normal development and tissue homeostasis
- It is mediated by various caspases and μgtimately results in the activation of endogenous endonucleases that degrade cellular DNA
- Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress
- Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis
- Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unknown
- It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.