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PIPA520159

Precerebellin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA520159-Each-of-1 In Stock ₹ 46,591.50

PIPA520159 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

Precerebellin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CBLN1

Gene Alias

[des-Ser1]CER; [des-Ser1]-cerebellin; AI323299; Brain protein D3; Cbln1; CER; Cerebellin; cerebellin 1 precursor; cerebellin 1 precursor protein; cerebellin-1; des-Ser(1)-cerebellin; des-Ser1-cerebellin; Precerebellin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12404, 498922, 869

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P23435, P63182, Q9R171

Gene Symbols

CBLN1

Immunogen

A 16 amino acid synthetic peptide from near the carboxy-terminus human precerebellin

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • A suggested positive control is 293 cell lysate
  • PA5-20159 can be used with blocking peptide PEP-0278
  • Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q
  • Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release
  • The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus
  • Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.