SLUG Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520290-Each-of-1 | In Stock | ₹ 49,617.50 |
PIPA520290 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,617.50
GST (18%): ₹ 8,931.15
Total Price: ₹ 58,548.65
Antigen
SLUG
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SNAI2
Gene Alias
MGC10182; neural crest transcription factor Slug; Protein snail homolog 2; SLUG; slug (chicken homolog), zinc finger protein; Slug, chicken homolog; Slugh; SLUGH1; Snai2; snail family transcriptional repressor 2; snail family zinc finger 2; snail homolog 2; Snail2; snail-like protein 2; WS2D; Zinc finger protein SNAI2; zinc finger transcription factor snail 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20583, 6591
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O43623, P97469
Gene Symbols
SNAI2
Immunogen
A 13 amino acid peptide from near the center of human Slug.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is 293 cell lysate
- PA5-20290 can be used with blocking peptide PEP-0420
- Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis
- Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta
- Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1
- More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival
- Furthermore, Slug can protect hemopoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family.