SUMO1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520300-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA520300 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
SUMO1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SUMO1
Gene Alias
CG4494-PA; DAP1; GAP modifying protein 1; GAP-modifying protein 1; GMP1; LD07775p; OFC10; OK/SW-cl.43; OTTHUMP00000202403; OTTHUMP00000202404; OTTHUMP00000202405; OTTHUMP00000202406; OTTHUMP00000202409; OTTHUMP00000202410; PIC1; SENP2; sentrin; Sentrin-1; small ubiquitin-like modifier 1; small ubiquitin-related modifier 1; small ubiquitin-related modifier-1; SMT3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 1 (yeast); Smt3C; Smt3h3; SMTP3; Sumo1; SUMO-1; SUMO-1 related peptidase; Ubiquitin-homology domain protein PIC1; ubiquitin-like 1; ubiquitin-like 1 (sentrin); ubiquitin-like protein SMT3C; Ubiquitin-like protein UBL1; UBL1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22218, 301442, 7341
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P63165, P63166, Q5I0H3
Gene Symbols
SUMO1
Immunogen
A 14 amino acid peptide from near the amino terminus of human sumo.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is HL60 cell lysate
- PA5-20300 can be used with blocking peptide PEP-0424
- SUMO1 is an ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer
- Covalent attachment, via an isopeptide bond, to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4
- This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction
- SUMO1 is involved, for instance, in targeting RANGAP1 to the nuclear pore complex protein RANBP2
- Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins
- SUMO1 may also regulate a network of genes involved in palate development
- Mutations in the gene can result in non-syndromic orofacial cleft 10.