CDNF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520429-Each-of-1 | In Stock | ₹ 47,926.50 |
PIPA520429 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,926.50
GST (18%): ₹ 8,626.77
Total Price: ₹ 56,553.27
Antigen
CDNF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdnf
Gene Alias
9330140G23; arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Cdnf; Cerebral dopamine neurotrophic factor; conserved dopamine neurotrophic factor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
227526, 361276, 441549
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P0C5I0, Q49AH0, Q8CC36
Gene Symbols
Cdnf
Immunogen
a 9 amino acid peptide from near the carboxy terminus of human CDNF.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse brain tissue lysate
- PA5-20429 can be used with blocking peptide PEP-0546
- The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor
- Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain
- Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease
- Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease
- At least two isoforms of CDNF are known to exist.