PIPA520593
PRTFDC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520593-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PRTFDC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRTFDC1
Gene Alias
HHGP; phosphoribosyl transferase domain containing 1; phosphoribosyltransferase domain-containing protein 1; PRTFDC1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
291355, 56952
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q9NRG1
Gene Symbols
PRTFDC1
Immunogen
A 14 amino acid peptide from near the center of human PRTFDC1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is human brain tissue lysate
- PA5-20593 can be used with blocking peptide PEP-0713
- Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene
- Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing
- Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth
- These results suggest that PRTFDC1 can act as a tumor-suppressor gene
- At least three isoforms of PRTFDC1 are known to exist.