PIPA520796
PALB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520796-Each-of-1 | In Stock | ₹ 48,994.50 |
PIPA520796 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,994.50
GST (18%): ₹ 8,819.01
Total Price: ₹ 57,813.51
Antigen
PALB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Palb2
Gene Alias
BC066140; FANCN; FLJ21816; PALB2; Partner and localizer of BRCA2; PNCA3; RGD1304759
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
233826, 293452, 79728
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q3U0P1, Q86YC2
Gene Symbols
Palb2
Immunogen
A 15 amino acid peptide from near the carboxy terminus of human PALB2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is SK-N-SH cell lysate
- PA5-20796 can be used with blocking peptide PEP-0910
- The breast cancer early onset proteins BRCA1 and BRCA2 are central to the repair of DNA damage by homologous recombination and are strongly associated with inherited breast and ovarian cancer
- The protein PALB2 is required for the localization of BRCA2 to sites of DNA damage and like BRCA1 and 2 is a breast cancer susceptibility gene
- PALB2 is thought to function through directly binding to BRCA1, which allows the PALB2 protein to organize BRCA2 and the recombinase RAD51 at the site of DNA damage
- Analysis of the BRCA1-PALB2-BRCA2-RAD51network may allow predictions to be made of the responsiveness of a particular tumor to therapeutic treatments
- At least four isoforms of PALB2 are known to exist.