JMJD1A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520802-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520802 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
JMJD1A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KDM3A
Gene Alias
1700105C21Rik; C230043E16Rik; DKFZp686A24246; DKFZp686P07111; JHDM2a; JHMD2A; JmjC domain-containing histone demethylation protein 2A; Jmjd1; Jmjd1a; jumonji C domain-containing histone demethylase 2A; jumonji domain containing 1A; jumonji domain-containing protein 1A; KDM2A; Kdm3a; Kiaa0742; lysine (K)-specific demethylase 3A; lysine demethylase 3A; lysine-specific demethylase 3A; probable zinc finger protein; testis specific gene A; testis-specific gene A protein; testis-specific protein A; TGSA; Tsga; zinc finger protein TSGA
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
104263, 312440, 55818
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q63679, Q6PCM1, Q9Y4C1
Gene Symbols
KDM3A
Immunogen
A 16 amino acid peptide from near the amino terminus of human JMJD1A.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse liver tissue lysate
- PA5-20802 can be used with blocking peptide PEP-0916
- JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code
- It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'
- Demethylation of Lys residue generates formaldehyde and succinate
- JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation
- It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin
- Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.