IA-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520823-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA520823 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
IA-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
INSM1
Gene Alias
IA1; IA-1; INSM transcriptional repressor 1; Insm1; insulinoma associated 1; insulinoma-associated 1; insulinoma-associated protein (IA-1); insulinoma-associated protein 1; insulinoma-associated protein 1-like; LOC100912563; Zinc finger protein IA-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100912563, 3642, 53626
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q01101, Q63ZV0
Gene Symbols
INSM1
Immunogen
A 19 amino acid peptide from near the amino terminus of human IA-1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is rat thymus tissue lysate
- PA5-20823 can be used with blocking peptide PEP-0937
- IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system
- Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb
- It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation
- IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.