EFHD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520919-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA520919 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
EFHD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Efhd2
Gene Alias
2600015J22Rik; AA408606; D4Wsu27e; EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain family member D2; EF-hand domain family, member D2; EF-hand domain-containing protein D2; Efhd2; MGC4342; RP3-467K16.3; swiprosin 1; swiprosin-1; Sws1; testicular tissue protein Li 62
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27984, 298609, 79180
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q4FZY0, Q96C19, Q9D8Y0
Gene Symbols
Efhd2
Immunogen
A 16 amino acid peptide near the amino terminus of human EFHD2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse brain tissue lysate
- PA5-20919 can be used with blocking peptide PEP-1033
- EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology
- EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells
- It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux
- EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis
- It controls spontaneous apoptosis through the regulation of BCL2L1 abundance
- Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.