APC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520944-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520944 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
APC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APC2
Gene Alias
9230107K09Rik; adenomatosis polyposis coli 2; adenomatous polyposis coli like; adenomatous polyposis coli protein 2; Adenomatous polyposis coli protein-like; AI852447; AL024279; Anapc2; anaphase promoting complex subunit 2; anaphase-promoting complex subunit 2; APC2; APC2, WNT signaling pathway regulator; APCL; APC-like; Cyclosome subunit 2; EGK_07151; Emi4; expressed during mesenchymal induction 4; Imi4; induced during mesenchymal induction 4; KIAA1406; mKIAA1406; R75424
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10297, 23805
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O95996, Q9Z1K7
Gene Symbols
APC2
Immunogen
An 18 amino acid peptide near the center of human APC2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is Hela cell lysate
- PA5-20944 can be used with blocking peptide PEP-1058
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis
- APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle
- APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence
- The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex
- Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.