TRIM71 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521011-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA521011 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TRIM71
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRIM71
Gene Alias
2610206G21Rik; abnormal cell LINeage LIN-41; AL022943; B-box zinc finger, Filamin and NHL repeat containing protein (123.8 kD) (lin-41); Drosophila dappled/ vertebrate TRipartite Motif protein related; E3 ubiquitin-protein ligase TRIM71; Gm1127; homolog of C. elegans Lin-41; Lin41; LIN-41; lin-41 homolog; mLin41; mLin-41; protein lin-41 homolog; RGD1566388; RING-type E3 ubiquitin transferase TRIM71; Trim71; tripartite motif containing 71; tripartite motif containing 71, E3 ubiquitin protein ligase; tripartite motif-containing 71; tripartite motif-containing protein 71
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
131405, 301042, 636931
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
D3ZVM4, Q1PSW8, Q2Q1W2
Gene Symbols
TRIM71
Immunogen
A 15 amino acid peptide near the carboxy terminus of human TRIM71.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is human brain tissue lysate
- PA5-21011 can be used with blocking peptide PEP-1125
- TRIM71 is the mammalian ortholog to the C
- elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways
- Similar to its C
- elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development
- Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4
- Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover
- Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.