KPNA6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521036-Each-of-1 | In Stock | ₹ 46,146.50 |
PIPA521036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,146.50
GST (18%): ₹ 8,306.37
Total Price: ₹ 54,452.87
Antigen
KPNA6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KPNA6
Gene Alias
FLJ11249; importin alpha 7 subunit; importin alpha-S2; Importin subunit alpha-7; importin-alpha-S2; IPOA7; karyopherin (importin) alpha 5; karyopherin (importin) alpha 6; karyopherin alpha 6; karyopherin alpha 6 (importin alpha 7); karyopherin subunit alpha 6; karyopherin subunit alpha-6; Kpna5; Kpna6; KPNA7; MGC17918; NPI-2; RP4-622L5.1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16650, 23633, 362607
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O35345, O60684
Gene Symbols
KPNA6
Immunogen
A 13 amino acid peptide near the amino terminus of human KPNA6.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is 293 cell lysate
- PA5-21036 can be used with blocking peptide PEP-1150
- Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism
- The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC
- KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6
- Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation, possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation
- KPNA6 also interacts with the Rev protein of HIV-1 and promote its nuclear import.