PIPA521068
SLC39A3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521068-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA521068 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SLC39A3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLC39A3
Gene Alias
AI845814; SLC39A3; solute carrier family 39 (zinc transporter), member 3; solute carrier family 39 member 3; Zinc transporter ZIP3; Zip3; ZIP-3; Zrt- and Irt-like protein 3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
106947, 29985
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q99K24, Q9BRY0
Gene Symbols
SLC39A3
Immunogen
A 16 amino acid peptide near the center of human ZIP3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse small intestine tissue lysate
- PA5-21068 can be used with blocking peptide PEP-1182
- The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters
- Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation
- Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice
- Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient
- More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.