ZBTB5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521085-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA521085 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ZBTB5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZBTB5
Gene Alias
5930421I10; 9430083K24Rik; AI646847; expressed in brain and neural tube; Kiaa0354; mKIAA0354; RP11-397D12.5; Transcription factor ZNF-POZ; ZBTB5; zinc finger and BTB domain containing 5; zinc finger and BTB domain-containing protein 5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
230119, 298084, 9925
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O15062, Q7TQG0
Gene Symbols
ZBTB5
Immunogen
A 16 amino acid peptide near the carboxy terminus of human ZBTB6.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse brain tissue lysate
- PA5-21085 can be used with blocking peptide PEP-1199
- The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain
- ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein
- Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21
- ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter
- ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.