PIPA521098
LRRTM3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521098-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA521098 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
LRRTM3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LRRTM3
Gene Alias
9630044H04Rik; leucine rich repeat transmembrane neuronal 3; leucine-rich repeat transmembrane neuronal protein 3; LRRTM3; UNQ803/PRO1693
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216028, 294380, 347731
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
D3ZAL8, Q86VH5, Q8BZ81
Gene Symbols
LRRTM3
Immunogen
An 18 amino acid peptide near the carboxy terminus of human LRRTM3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse brain tissue lysate
- PA5-21098 can be used with blocking peptide PEP-1212
- The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation
- Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the A-beta42 peptide that is the main component of amyloid plaques
- Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma A-beta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.