PIPA521116

MYZAP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521116-Each-of-1 In Stock ₹ 47,481.50

PIPA521116 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

MYZAP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYZAP

Gene Alias

AA407270; AV006038; gcom; GCOM1; Gcom2; Gm640; GRINL1A; GRINL1A combined protein; GRINL1A complex locus 1; GRINL1A complex locus protein 1; GRINL1A complex locus upstream; GRINL1A upstream protein; Grinl1a7; Gup; myocardial intercalated disc protein; myocardial zonula adherens protein; myocardium-enriched ZO1-associated protein; myocardium-enriched zonula adherens protein; myocardium-enriched zonula occludens-1-associated protein; myozap; Myzap; MYZAP-POLR2M

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100820829, 102371, 363091

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P0CAP1, Q3UIJ9, Q5EB94

Gene Symbols

MYZAP

Immunogen

An 18 amino acid peptide near the carboxy terminus of human MYOZAP.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is rat kidney tissue lysate
  • PA5-21116 can be used with blocking peptide PEP-1230
  • MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein
  • It is strongly expressed in the heart and lung and is a novel component of intercalated disc
  • MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling
  • Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction
  • The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A)
  • Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.