PIPA521133

ZMIZ1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521133-Each-of-1 In Stock ₹ 46,502.50

PIPA521133 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ZMIZ1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZMIZ1

Gene Alias

BC065120; E330020C23; ENSMUSG00000072684; FLJ00092 protein; Gm10397; hZIMP10; I920194n01; KIAA1224; MIZ; PIAS-like protein Zimp10; Rai17; retinoic acid induced 17; retinoic acid-induced protein 17; RP11-519K18.1; TRAFIP10; Zimp10; Zinc finger MIZ domain-containing protein 1; zinc finger MIZ-type containing 1; zinc finger, MIZ-type containing 1; zinc finger-containing, Miz1, PIAS-like protein on chromosome 10; ZMIZ1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57178

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9ULJ6

Gene Symbols

ZMIZ1

Immunogen

A 15 amino acid peptide near the amino terminus of human ZIMP10.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is K562 cell lysate
  • PA5-21133 can be used with blocking peptide PEP-1247
  • Retinoic acid plays a critical role in development, cellular growth, and differentiation and induces the expression of a variety of genes
  • RAI17 expression is induced by retinoic acid and is predominantly expressed in heart, brain and ovaries
  • Within brain, highest expression is in amygdala
  • The deduced 1,067-amino acid protein contains an MSX-interacting zinc finger (MIZ) domain, a nuclear localization signal sequence, and 2 proline-rich regions
  • A strong intrinsic transactivation domain is identified in the C-terminal proline-rich region
  • RAI17 expression is detected in various cancer cell lines
  • RAI17 colocalizes with endogenous androgen receptor (AR) in the nuclei of prostate epithelial cells from human tissue samples
  • In human prostate cancer cells, RAI17 increases the transcriptional activity of AR
  • Studies using sumoylation-deficient AR mutants suggest that the increase of AR activity by RAI17 is dependent upon receptor sumoylation.