PIPA521169

CCDC141 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521169-Each-of-1 In Stock ₹ 47,036.50

PIPA521169 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

CCDC141

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CCDC141

Gene Alias

2610301F02Rik; CAMDI; CCDC141; coiled-coil domain containing 141; coiled-coil domain-containing protein 141; Coiled-coil protein associated with myosin II and DISC1; ENSMUSG00000075261

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

285025, 545428

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q6ZP82

Gene Symbols

CCDC141

Immunogen

An 18 amino acid peptide near the amino terminus of human CCDC141.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is SK-N-SH cell lysate
  • PA5-21169 can be used with blocking peptide PEP-1283
  • Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II
  • CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner
  • Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.