PIPA521387

ENO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521387-Each-of-1 In Stock ₹ 49,439.50

PIPA521387 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

ENO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ENO1

Gene Alias

0610008I15; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydro-lyase; AL022784; alpha enolase; alpha enolase like 1; alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; c-Myc promoter binding protein; C-myc promoter-binding protein; Eno1; Eno-1; ENO1L1; enoa; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase-alpha; epididymis secretory protein Li 17; HEL-S-17; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13806, 2023

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Dot Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P06733, P17182

Gene Symbols

ENO1

Immunogen

Recombinant fragment corresponding to a region within amino acids 199 and 434 of ENO1 (Uniprot ID#P06733)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain
  • Predicted reactivity: Mouse (94%), Rat (93%), Xenopus laevis (90%), Chicken (93%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (93%), Guinea pig (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate
  • It comprises three distinct subunits, alpha, beta and gamma
  • Non Neuronal Enolase(ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits
  • The gene for ENO1 also encodes a shorter monomeric structural lens protein, tau-crystallin
  • Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses
  • May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons
  • Stimulates immunoglobulin production.Used as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest
  • Also marker for endometriosis
  • Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies
  • Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT)
  • HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.