PIPA521417

REA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521417-Each-of-1 In Stock ₹ 46,502.50

PIPA521417 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

REA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PHB2

Gene Alias

AU044498; BAP; Bap37; Bap-37; Bcap27; BCAP37; B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; MGC117268; p22; phb2; phb2 {ECO:0000250; PNAS-141; prohibitin 2; prohibitin-2; Rea; Repressor of estrogen receptor activity; UniProtKB:Q99623}

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11331, 114766, 12034

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.66 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O35129, Q5XIH7, Q99623

Gene Symbols

PHB2

Immunogen

Recombinant fragment corresponding to a region within amino acids 45 and 299 of Prohibitin 2 (Uniprot ID#Q99623)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: H1299, HeLa, mouse brain
  • Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (87%), Pig (98%), Chicken (95%), Rhesus Monkey (100%), Bovine (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases
  • This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens
  • It competes with NCOA1 for modulation of ER transcriptional activity
  • It is probably involved in regulating mitochondrial respiration activity and in aging.