FANCD2 Polyclonal Antibody, HRP, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA522707-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA522707 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
FANCD2
Classification
Polyclonal
Conjugate
HRP
Gene
FANCD2
Gene Alias
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
211651, 2177, 312641, 394241, 484659
Content And Storage
4° C, store in dark
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.82 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q6IV68, Q80V62, Q9BXW9
Gene Symbols
FANCD2
Immunogen
Human FANCD2 fusion protein (N-terminal fragment).
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Avian, Canine, Human, Marsupial, Mouse, Non-human Primate, Rat, Zebrafish
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot, this antibody should recognize a band at ∽166 kDa (post-translationally modified form)
- Additional bands may be seen at lower molecular weights
- FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
- It promotes accurate and efficient pairing of homologs during meiosis
- FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
- It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
- FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
- Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
- This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.