CRACC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525589-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA525589 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
CRACC
Classification
Polyclonal
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q9NQ25
Gene Symbols
SLAMF7
Immunogen
KLH conjugated synthetic peptide between 58-85 amino acids from the central region of human SLAMF7
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
SLAMF7
Gene Alias
19A; 19A24; 19A24 protein; 4930560D03Rik; CD2 subset 1; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; CD319; CRACC; CS1; Leukocyte cell-surface antigen; membrane protein FOAP-12; Novel Ly9; novel LY9 (lymphocyte antigen 9) like protein; protein 19A; RGD1560190; SLAM family member 7; SLAMF7; UNQ576/PRO1138
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
57823
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain
- Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway
- It may play a role in lymphocyte adhesion
- Isoform 3 does not mediate any activation
- SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro)
- SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea
- Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines
- The isoform 3 is expressed at much lower level than isoform 1
- There are three named isoforms.