Calpain 3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA526818-Each-of-1 | In Stock | ₹ 47,659.50 |
PIPA526818 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,659.50
GST (18%): ₹ 8,578.71
Total Price: ₹ 56,238.21
Antigen
Calpain 3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Capn3
Gene Alias
AI323605; calcium-activated neutral proteinase 3; calpain 3; calpain 3, (p94); calpain L3; Calpain p94; calpain p94, large [catalytic] subunit; calpain, large polypeptide L3; calpain-3; CANP 3; CANP3; CANPL3; Capa3; Capa-3; CAPN 3; CAPN3; LGMD 2A; LGMD2; LGMD2A; Lp82; Lp84; Lp85; MGC10767; MGC11121; MGC14344; MGC4403; Muscle-specific calcium-activated neutral protease 3; muscle-specific calcium-activated neutral protease 3 large subunit; NCL1; nCL-1; New calpain 1; p94; skeletal muscle specific calpain p94
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
825
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P20807
Gene Symbols
Capn3
Immunogen
KLH conjugated synthetic peptide between 603-632 amino acids from the C-terminal region of human CAPN3
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with non-human primate based on sequence homology
- Calpain, an intracellular calcium-dependent protease that cleaves cytoskeletal and submembranous proteins, plays a role in cytoskeletal reorganization and muscle protein degradation
- Calpain is a heterodimer composed of a small regulatory subunit and one of three large catalytic subunits, designated calpain 1, calpain 2 and calpain 3
- Calpain 3 (calpain p94) is a muscle-preferred calcium activated neutral protease that localizes to the nucleus
- Mutations involving the calpain 3 gene are associated with limb-girdle muscle dystrophy type 2A, a form of autosomal recessive and progressive neuromuscular diso4
- Calpastatin regulates calpain by inhibiting both the proteolytic activity of calpain and its binding to membranes
- Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing.