TDP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527111-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA527111 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TDP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tdp1
Gene Alias
2810481F14Rik; 4921509N21Rik; AI838772; AW493413; E430034L06Rik; MLZ-501; protein expressed in male leptotene and zygotene spermatocytes 501; SCAN1; Tdp1; Tyr-DNA phosphodiesterase 1; tyrosyl-DNA phodphodiesterase 1; tyrosyl-DNA phosphodiesterase 1; Tyrosyl-DNA phosphodiesterase 1-like protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55775
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NUW8
Gene Symbols
Tdp1
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 259 of Human TDP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Predicted reactivity: Rhesus Monkey (93%), Chimpanzee (97%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA
- This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks
- This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains
- Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1)
- While several transcript variants may exist for this gene, the full-length natures of only two have been described to date
- These two represent the major variants of this gene and encode the same isoform.