JIP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527224-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA527224 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
JIP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPK8IP1
Gene Alias
C-Jun-amino-terminal kinase-interacting protein 1; Ib1; IB-1; Islet-brain 1; islet-brain-1; JIP1; JIP-1; JIP-1-related protein; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; JRP; Mapk8ip; Mapk8ip1; mitogen activated protein kinase 8 interacting protein; mitogen activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8-interacting protein 1; mjip-2a; PRKM8 interacting protein; PRKM8IP; protein kinase, mitogen-activated 8 interacting protein; Skip
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19099, 9479
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UQF2, Q9WVI9
Gene Symbols
MAPK8IP1
Immunogen
Recombinant fragment corresponding to a region within amino acids 112 and 510 of Human JIP-1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HepG2
- Predicted reactivity: Mouse (94%), Rat (94%), Bovine (94%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene is a regulator of the pancreatic beta-cell function
- It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8)
- This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells
- This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2
- RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells
- This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.