MMP12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527254-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA527254 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
MMP12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mmp12
Gene Alias
3.4.24.65; AV378681; HME; Macrophage elastase; macrophage metalloelastase; macrophage-metalloelastase; matrix metallo protease; matrix metallopeptidase 12; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12; matrix metalloproteinase 12 (macrophage elastase); matrix metalloproteinase-12; ME; MGC138506; MME; Mmel; MMP; Mmp12; MMP-12; MMPs
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4321
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P39900
Gene Symbols
Mmp12
Immunogen
Synthetic peptide corresponding to a region within amino acids 213 and 307 of Human MMP12
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, H1299, HelaS3
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis
- Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases
- It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described
- The enzyme degrades soluble and insoluble elastin
- It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema
- The gene is part of a cluster of MMP genes which localize to chromosome 11q22
- 3.