CD51 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527272-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA527272 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
CD51
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGAV
Gene Alias
1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen identified by monoclonal antibody L230; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; integrin alpha V; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin subunit alpha V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; ITGB3; MSK8; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; VNR; VNRA; VTNR
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16410, 3685
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.58 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P06756, P43406
Gene Symbols
ITGAV
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 722 and 944 of Human Integrin alpha V
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: RD (Rhabdomyosarcoma) cell (Mock control), RD transfected scramble siRNA, HUVEC
- Predicted reactivity: Mouse (88%), Pig (92%), Sheep (90%), Rhesus Monkey (99%), Bovine (91%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ITAGV encodes integrin alpha chain V
- Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
- The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins
- Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR)
- In addition to adhesion, many integrins are known to facilitate signal transduction
- The ITGB3 protein product is the integrin beta chain beta 3
- Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
- A given chain may combine with multiple partners resulting in different integrins
- Integrin beta 3 is found along with the alpha IIb chain in platelets
- Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.