Angiopoietin 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527297-Each-of-1 | In Stock | ₹ 49,172.50 |
PIPA527297 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,172.50
GST (18%): ₹ 8,851.05
Total Price: ₹ 58,023.55
Antigen
Angiopoietin 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ANGPT2
Gene Alias
AGPT2; Ang2; Ang-2; angiopoietin 2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; ANGPT2; endothelial growth factor; Tie2-ligand
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11601, 285, 89805
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.04 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O15123, O35462, O35608
Gene Symbols
ANGPT2
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 496 of Human Angiopoietin 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HUVEC
- Predicted reactivity: Mouse (84%), Rat (86%), Dog (92%), Pig (92%), Chicken (85%), Bovine (89%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ANG-2 binds to the endothelial cell specific receptor Tie-2, but, in contrast to ANG-1, does not induce tyrosine phosphorylation
- Consequently, ANG-2 modulates ANG-1 activation of Tie-2 and, depending on the physiological and biochemical environment, can act either as an agonist or antagonist of Tie-2 induced angiogenesis
- The signaling interactions of ANG-1, ANG-2 and Tie-2, along with less characterized ANG-3 and ANG-4, are required for embryonic and adult angiogenesis
- Physiologically, ANG-1 and ANG-2 are associated with sprouting, tube formation, and structural integrity of newly formed blood vessels
- Mature human ANG-2 is a secreted protein containing 480 amino acid residues
- ANG-2 is composed of an alpha-helix-rich coiled coil N-terminal domain and fibrinogen-like C-terminal domain
- ANG-2 exists predominantly in the form of a disulfide-linked dimer.