eIF3d Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527411-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA527411 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
eIF3d
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EIF3D
Gene Alias
66/67kDa; AA407891; actinin alpha 4; ACTININ-4; Actn4; alpha actinin 4; alpha-actinin-4; eIF3 p66; EIF3D; eIF3d {ECO:0000255; eIF3p66; eIF3-p66; Eif3s7; eIF-3-zeta; eIF3-zeta; eIF-3-zeta {ECO:0000255; eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D {ECO:0000255; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta; eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3, subunit D; F-actin cross-linking protein; focal segmental glomerulosclerosis 1; FSGS; FSGS1; HAMAP-Rule:MF_03003}; non-muscle alpha-actinin 4; RP5-1119A7.12-003; si:dkey-165I8.6; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit; wu:fb12a03; zgc:64097
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
362952, 55944, 8664
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.63 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O15371, O70194, Q6AYK8
Gene Symbols
EIF3D
Immunogen
Recombinant fragment corresponding to a region within amino acids 241 and 528 of Human EIF3 zeta
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLaS3, mouse liver, PC-12, Rat2
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (92%), Xenopus laevis (91%), Pig (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3)
- eIF3 is a multiprotein complex composed of at least 13 different subunits
- eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state
- An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding
- eIF3D is the major RNA binding subunit of the eIF3 complex
- It associates with the subunit p170 of eIF-3
- Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.