PIPA527435

ENSA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527435-Each-of-1 In Stock ₹ 46,858.50

PIPA527435 - Each of 1

₹ 46,858.50

In Stock

Quantity

1

Base Price: ₹ 46,858.50

GST (18%): ₹ 8,434.53

Total Price: ₹ 55,293.03

Antigen

ENSA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ENSA

Gene Alias

1700020C18Rik; 2610007F17Rik; AI451924; Alpha-endosulfine; ARPP-19e; endosulfine alpha; endosulfine-alpha variant 1; endosulfine-alpha variant 3; ENSA

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2029, 56205, 60334

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.6 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O43768, P60840, P60841

Gene Symbols

ENSA

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 121 of Human ENSA

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T
  • Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (90%), Pig (100%), Chicken (92%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family
  • This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1
  • ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells
  • This protein is thought to be an endogenous regulator of KATP channels
  • In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes
  • At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.