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PIPA527721

Calpain 3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA527721-Each-of-1 In Stock ₹ 46,146.50

PIPA527721 - Each of 1

₹ 46,146.50

In Stock

Quantity

1

Base Price: ₹ 46,146.50

GST (18%): ₹ 8,306.37

Total Price: ₹ 54,452.87

Antigen

Calpain 3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Capn3

Gene Alias

AI323605; calcium-activated neutral proteinase 3; calpain 3; calpain 3, (p94); calpain L3; Calpain p94; calpain p94, large [catalytic] subunit; calpain, large polypeptide L3; calpain-3; CANP 3; CANP3; CANPL3; Capa3; Capa-3; CAPN 3; CAPN3; LGMD 2A; LGMD2; LGMD2A; Lp82; Lp84; Lp85; MGC10767; MGC11121; MGC14344; MGC4403; Muscle-specific calcium-activated neutral protease 3; muscle-specific calcium-activated neutral protease 3 large subunit; NCL1; nCL-1; New calpain 1; p94; skeletal muscle specific calpain p94

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

825

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

2 mg/mL

Formulation

PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P20807

Gene Symbols

Capn3

Immunogen

Recombinant fragment corresponding to a region within amino acids 623 and 821 of Human Calpain 3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: HeLa
  • Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (82%), Pig (94%), Rabbit (89%), Chicken (86%), Sheep (94%), Bovine (93%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Calpain, an intracellular calcium-dependent protease that cleaves cytoskeletal and submembranous proteins, plays a role in cytoskeletal reorganization and muscle protein degradation
  • Calpain is a heterodimer composed of a small regulatory subunit and one of three large catalytic subunits, designated calpain 1, calpain 2 and calpain 3
  • Calpain 3 (calpain p94) is a muscle-preferred calcium activated neutral protease that localizes to the nucleus
  • Mutations involving the calpain 3 gene are associated with limb-girdle muscle dystrophy type 2A, a form of autosomal recessive and progressive neuromuscular diso4
  • Calpastatin regulates calpain by inhibiting both the proteolytic activity of calpain and its binding to membranes
  • Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing.